The Safeguard Iowa Partnership is a voluntary coalition of the state's business and government leaders, who share a commitment to working together to prevent, prepare for, respond to, and recover from catastrophic events in Iowa. Created in 2007 by the Iowa Business Council and representatives from key state agencies, the partnership will help integrate business resources, expertise, and response plans with those of government during all stages of disaster management.

Safeguard Iowa Partnership became an Iowa nonprofit corporation on July 25, 2008 and granted 501(c)(3) tax status from the Internal Revenue Service. Additionally, Safeguard Iowa Partnership is registered with the Iowa Register of Accountability as a nonprofit committed to continuous improvement through the Principles and Practices for Charitable Nonprofit Excellence.